Chirurgia radicale verso conservativa per il tumore dello stomaco e consulenza ad altri progetti di epidemiologia clinica in ambito gastroenterologico

Conservative versus radical surgery for stomach cancer and clinical epidemiology consulting in other projects in gastroenterology

OBIETTIVI E SVILUPPO DEL PROGETTO

Confrontare la frequenza di complicanze e la sopravvivenza tra linfoadenectomia standard (D1) e linfoadenectomnia radicale (D2) per il tumore dello stomaco.

MATERIALI E METODI

- Studio dimostrativo su D2 su una serie selezionata di pazienti;
- trial randomizzato di confronto tra le due metodiche.

RISORSE E FINANZIAMENTI

Ricerca sanitaria finalizzata regionale 2003 e 2010.

COLLABORATORI

Nereo SEGNAN

Carlo SENORE

Manuela CECCARELLI

Silvia PATRIARCA

Mariano TOMATIS

Denis CASELLA

Roberto ZANETTI

PUBBLICAZIONI

- DEGIULI M, SASAKO M, PONTI A, PONZETTO A, SOLDATI T, DANESE F, CALVO F. Morbidity and mortality after D2 gastrectomy for gastric cancer: results of the italian gastric cancer study group prospective multicenter surgical study. J Clinical Onc 1998; 16: 1-6.
- DEGIULI M, SASAKO M, CALGARO M, GARINO M, REBECCHI F, MINECCIA M, SCAGLIONE D, ANDREONE D, PONTI A, CALVO F. Morbidity and mortality after D1 and D2 gastrectomy for cancer: Interim analysis of the Italian Gastric Cancer Study Group (IGCSG) randomised surgical trial. Eur J Surg Oncol 2004; 30: 303-8.
- DEGIULI M, SASAKO M, PONTI A, CALVO F. Survival results of a multicentre phase II study to evaluate D2 gastrectomy for gastric cancer. Br J Cancer 2004; 90: 1727-32.
- PISANI P, PONTI A. Screening for gastric cancer. In: Degiuli M. (editor): Management of Gastric cancer. Recent advances. Minerva Medica Ed, Turin, 2008; 15-23.
- Vigano L, Laurent A, Tayar C, Tomatis M, Ponti A, Cherqui D. The learning curve in laparoscopic liver resection: improved feasibility and reproducibility. Ann Surg. 2009; 250: 772-82.
- Degiuli M, Sasako M, Ponti A; Italian Gastric Cancer Study Group. Morbidity and mortality in the Italian Gastric Cancer Study Group randomized clinical trial of D1 versus D2 resection for gastric cancer. Br J Surg 2010; 97: 643-9.
- Ribero D, Nuzzo G, Amisano M, Tomatis M, Guglielmi A, Giulini SM, Aldrighetti L, Calise F, Gerunda GE, Pinna AD, Capussotti L. Comparison of the prognostic accuracy of the sixth and seventh editions of the TNM classification for intrahepatic cholangiocarcinoma. HPB (Oxford) 2011; 13: 198-205.
- Degiuli M, Borasi A, Forchino F, Marano A, Vendrame A, Casella D, Ponti A, Mussa B, Sandrucci S. Lymph-nodal ratio in gastric cancer staging system. Minerva Chir 2011; 66: 177-82.
- Ribero D, Pinna AD, Guglielmi A, Ponti A, Nuzzo G, Giulini SM, Aldrighetti L, Calise F, Gerunda GE, Tomatis M, Amisano M, Berloco P, Torzilli G, Capussotti L; for the Italian Intrahepatic Cholangiocarcinoma Study Group. Surgical Approach for Long-term Survival of Patients With Intrahepatic Cholangiocarcinoma: A Multi-Institutional Analysis of 434 Patients. Arch Surg 2012; 147: 1107-13.
. Randomized clinical trial comparing survival after D1 or D2 gastrectomy for gastric cancer. Degiuli M, Sasako M, Ponti A, Vendrame A, Tomatis M, Mazza C, Borasi A, Capussotti L, Fronda G, Morino M; Italian Gastric Cancer Study Group. Br J Surg. 2014 Jan;101(2):23-31. doi: 10.1002/bjs.9345.